Research Insights

This section focuses on recent global studies and discoveries in the various fields of healthcare.

Influence of Gadolinium, Field-strength and Sequence Type on Quantified Perfusion Values in Phase-resolved Functional Lung Mri

The purpose of this study is to evaluate the influences of gadoliniumbased contrast agents fieldstrength and different sequences on perfusion quantification in PhaseResolved Functional Lung PREFUL MRI

Effects of Low Versus High Inspired Oxygen Fraction on Myocardial Injury After Transcatheter Aortic Valve Implantation: a Randomized Clinical Trial

Oxygen therapy is used in various clinical situation but its clinical outcomes are inconsistent The relationship between the fraction of inspired oxygen FIO during transcatheter aortic valve

Effect of Any Form of Steroids in Comparison With That of Other Medications on the Duration of Olfactory Dysfunction in Patients With Covid-19

The life quality of about twothirds of patients with COVID is affected by related olfactory dysfunctions The negative impact of olfactory dysfunction ranged from the decreased pleasure of eating to impaired quality of life

Electronic Health Record-based Readmission Risk Model Performance for Patients Undergoing Outpatient Parenteral Antibiotic Therapy (Opat)

Outpatient Parenteral Antibiotic Therapy OPAT provides coordinated services to deliver parenteral antibiotics outside of the acute care setting However the reduction in monitoring and supervision may impact the risks of readmission to the hospital

Lumicitabine, an Orally Administered Nucleoside Analog, in Infants Hospitalized With Respiratory Syncytial Virus (Rsv) Infection: Safety, Efficacy, and Pharmacokinetic Results

Respiratory syncytial virus RSV infection is the leading cause of infant hospitalizations and mortality Lumicitabine an oral nucleoside analog was studied for the treatment of RSV The phase b and phase b studies reported here assessed the safety

Ethical Challenges of Using Remote Monitoring Technologies for Clinical Research: a Case Study of the Role of Local Research Ethics Committees in the Radar-ad Study

Clinical research with remote monitoring technologies RMTs has multiple advantages over standard paperpencil tests but also raises several ethical concerns While several studies have addressed the issue of governance of big data in clinical research

Loss of Sting in Parkin Mutant Flies Suppresses Muscle Defects and Mitochondria Damage

The early pathogenesis and underlying molecular causes of motor neuron degeneration in Parkinsons Disease PD remains unresolved In the model organism Drosophila melanogaster loss of the earlyonset PD gene parkin the ortholog of human PRKN results

Incidence, Prevalence, and Treatment of Anemia of Non-dialysis-dependent Chronic Kidney Disease: a Retrospective Database Study in France

Minimal data are available regarding the prevalence and incidence of anemia among patients with nondialysisdependent chronic kidney disease NDDCKD in France This was a retrospective noninterventional study of patients with a record of NDDCKD in the Echantillon

The Vipr2-selective Antagonist Ks-133 Changes Macrophage Polarization and Exerts Potent Anti-tumor Effects as a Single Agent and in Combination With an Anti-pd-1 Antibody

We have previously demonstrated that KS is a specific and potent antagonist of vasoactive intestinal peptide receptor VIPR We have also shown that vasoactive intestinal peptideVIPR signaling affects the polarity and activation of tumorassociated macrophages

Quality of Life, Self-reported Outcomes and Impact of Education Among People With Moderate and Severe Hemophilia A: an Integrated Perspective From a Latin American Country

Collecting and interpreting selfreported outcomes among people with hemophilia A supports the understanding of the burden of the disease and its treatment to improve holistic care However in Colombia this information is limited