Research Insights in American hhm – American Healthcare Magazine

Discovery of Neutralizing Sars-cov-2 Antibodies Enriched in a Unique Antigen Specific B Cell Cluster

Despite development of effective SARSCoV vaccines a subgroup of vaccine nonresponders depends on therapeutic antibodies or smallmolecule drugs in cases of severe disease

Clinical and Financial Outcomes of Hospitalizations for Cardiac Device Infection During the Covid-19 Pandemic in the Us

Cardiac device infection CDI can occur in up to of patients after device placement with mortality rates exceeding Although device removal is standard management

Noncanonical Rab9a Action Supports Retromer-mediated Endosomal Exit of Human Papillomavirus During Virus Entry

Rab GTPases play key roles in controlling intracellular vesicular transport GTPbound Rab proteins support vesicle trafficking Here we report that unlike cellular protein cargos retromermediated delivery of human papillomaviruses

Machine Learning Prediction of the Total Duration of Invasive and Non-invasive Ventilation During Icu Stay

Predicting the duration of ventilation in the ICU helps in assessing the risk of ventilatorinduced lung injury ensuring sufficient oxygenation and optimizing resource allocation

Impact of Covid-19 Pandemic on Pharmacologic Treatment of Patients Newly Diagnosed With Osteoporosis

This study determined whether initiation of pharmacologic treatment was delayed for newly diagnosed osteoporosis patients during the COVID pandemic

Short Dual Antiplatelet Therapy Duration After Percutaneous Coronary Intervention in High Bleeding Risk Patients: Systematic Review and Meta-analysis

Dual antiplatelet therapy DAPT following percutaneous coronary intervention PCI reduces major adverse cardiovascular events MACE and stent thrombosis However DAPT duration is a concern in high bleeding risk HBR patients

The ∆pv-aco2/∆ca-vo2 Ratio as a Predictor of Mortality in Patients With Severe Acute Respiratory Distress Syndrome Related to Covid-19

To evaluate the central venoustoarterial carbon dioxide difference combined with arterialtovenous oxygen content difference PvaCOCavO ratio as a predictor of mortality in patients with COVIDrelated severe acute respiratory distress syndrome ARDS

Validation of Reference Gene Stability for Mirna Quantification by Reverse Transcription Quantitative Pcr in the Peripheral Blood of Patients With Covid-19 Critical Illness

The COVID pandemic has created an urgency to study the host gene response that leads to variable clinical presentations of the disease particularly the critical illness response miRNAs have been implicated in the mechanism

Prevalence and Persistence of Cost-related Medication Non-adherence Before and During the Covid-19 Pandemic Among Medicare Patients at High Risk of Hospitalization

Nonadherence to medication due to cost is a serious challenge in the US healthcare system as one in four adults in the US have a difficult time affording their medications The COVID pandemic has imposed an unprecedented burden

Correlation of a Commercial Platform’s Results With Post-vaccination Sars-cov-2 Neutralizing Antibody Response and Clinical Host Factors

The objective of this study was to describe the correlation between the commercially available assay for antiSRBD IgG and protective serum neutralizing antibodies nAb against SARSCoV in an adult population after SARSCoV vaccination and determine if clinical variables impact this correlation