Research Insights

This section focuses on recent global studies and discoveries in the various fields of healthcare.

Identification of Molecularly Unique Tumor-Associated Mesenchymal Stromal Cells in Breast Cancer Patients

The tumor microenvironment is a complex mixture of cell types that bidirectionally interact and influence tumor initiation progression recurrence and patient survival Mesenchymal stromal cells MSCs of the tumor microenvironment engage in crosstalk with cancer cells to mediate epigenetic control of gene expression We identified CD MSCs residing

Risk Factors of Catheter- Associated Bloodstream Infection: Systematic Review and Meta-Analysis

The prevalence of catheterassociated bloodstream infections CLABSI is high and is a severe health problem associated with an increase in mortality and elevated economic costs There are discrepancies related to the risk factors of CLABSI since the results published are very heterogeneous

Circulating Long Non-coding Rnas as Novel Diagnostic Biomarkers for Alzheimer’s Disease (Ad): A Systematic Review and Meta-Analysis

Long noncoding RNAs lncRNAs have been reported to be involved in the pathogenesis of neurodegenerative diseases It has also been hypothesized that plasma exosomal lncRNAs may be used as Alzheimers disease AD biomarkers In this systematic review we compiled all studies on the subject

Association of Lymphopenia and Rdw Elevation With Risk of Mortality in Acute Aortic Dissection

The study aimed to investigate whether lymphopenia and red blood cell distribution width RDW elevation are associated with an increased risk of mortality in acute aortic dissection AAD Acute aortic dissection AAD is a potentially lethal condition with high morbidity and mortality Despite remarkable progress in diagnostic and therapeutic technique...

A Systematic Review to Explore How Exercise-based Physiotherapy via Telemedicine Can Promote Health Related Benefits for People With Cystic Fibrosis

To conduct a systematic review to evaluate the effects of physiotherapy exercises delivered via telemedicine on lung function and qualityoflife in people with Cystic Fibrosis CF The databases AMED CINAHL and MEDLINE were searched from December until December Reference lists of included studies were handsearched

Performance Evaluation Methods for Improvements at Post-market of Artificial Intelligence/machine Learning-based Computer-aided Detection/diagnosis/triage in the United States

Computeraided detection CADe computeraided diagnosis CADx and computeraided simple triage CAST which incorporate artificial intelligence AI and machine learning ML are continually undergoing postmarket improvement Therefore understanding the evaluation and approval process of improved products is important This study intended to conduct

Benefit of Stereoscopic Volume Rendering for the Identification of Pediatric Pulmonary Vein Stenosis From Ct Angiography

The use of threedimensional D technologies in medical practice is increasing however its use is largely untested One D technology stereoscopic volumerendered D display can improve depth perception Pulmonary vein stenosis PVS is a rare cardiovascular pathology often diagnosed by computed tomography

Audit Of Follow-up Of Mothers With Gestational Diabetes Mellitus

Women with gestational diabetes should get specialized advice and treatment as soon as possible and should be assessed by specialists of the diabetes and prenatal team within one week after being diagnosed The team should advise the lady on why gestational diabetes arises possible risks and consequences and therapies

Risk factors for disease severity and increased medical resource utilization in respiratory syncytial virus (+) hospitalized children

We aimed to provide regional data on clinical symptoms medical resource utilization MRU and risk factors for increased MRU in hospitalized respiratory syncytial virus RSVinfected Belgian pediatric population RSV is a common cause of respiratory tract infection in infants and young children and was estimated to be responsible yearly

Potential role of conventional and speckle-tracking echocardiography in the screening of structural and functional cardiac abnormalities in elderly individuals

Elderly individuals occupy an increasing part of the general population Conventional and speckletracking transthoracic echocardiography may help guide risk stratification in these individuals The purpose of this study was to evaluate the potential utility of conventional and speckletracking echocardiography