Chao Gao, Yuchuan Yue, Dongmei Wu, Junming Zhang, Shuyao Zhu.
Abstract
With the increasing utilization of cardiac rehabilitation in clinical treatment and prognosis for patients with cardiovascular diseases, exercise training has become a crucial component. High-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) are commonly employed in rehabilitating patients with cardiovascular diseases.
Introduction
The incidence and mortality of cardio vascular diseases (CVD) have been steadily increasing over the years [1]. According to a study on the global burden of cardiovascular diseases and risk factors, the total incidence of cardiovascular diseases has risen from 271 million in 1990 to 523 million in 2019.
Methods
The Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines were followed for the methodology of this review (S1 File). The complete protocol of this meta-analysis was uploaded and registered on the PROSPERO platform with the registration number:CRD42024532872.
Results
A total of 1432 articles were searched, and after repeated checks, 1112 were retained. Subsequently, the articles underwent pre-screening by reading the title and abstract.
Discussion
In this systematic review, we included 22 randomized controlled trials involving a total of 1364 patients and found that HIIT had better effects on improving PeakVO2, 6MWT, and PHR than MICT in patients with coronary artery disease. However, there was no significant difference in LVEF, LVEDV, and SBP.
Conclusion
The results of this systematic review showed that compared to MICT, HIIT had a greater improvement on PeakVO2 among CAD patients. Furthermore, HIIT seemed unaffected by intervention duration, exercise mode, frequency or exercise session when it came to enhancing PeakVO2.
Citation: Gao C, Yue Y, Wu D, Zhang J, Zhu S (2025) Effects of high-intensity interval training versus moderate-intensity continuous training on cardiorespiratory and exercise capacity in patients with coronary artery disease: A systematic review and meta-analysis. PLoS ONE 20(2): e0314134. https://doi.org/10.1371/journal.pone.0314134
Editor: Jeremy B. Coquart, Université de Lille: Universite de Lille, FRANCE
Received: August 20, 2024; Accepted: November 5, 2024; Published: February 20, 2025
Copyright: © 2025 Gao et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: All relevant data are within the paper and its Supporting Information files.
Funding: Project number: XJLL2023007; Funded by: The Fourth People's Hospital of Chengdu; Sponsor: Dongmei Wu(Writing – original draft);Yuchuan Yue (Preparation of the manuscript).
Competing interests: The authors have declared that no competing interests exist.
