Ganhui Wei, Jiacheng Zhang, Xiaowei Qiu
Abstract
The purpose of this study was to explore the auxiliary diagnostic value of volumetric CT value in quantifying the activity of a pulmonary tuberculoma.
Introduction
Tuberculosis is one of the top ten lethal medical conditions worldwide. According to the 2022 World Health Organization Global Tuberculosis Report [1], there were approximately 10.6 million new tuberculosis patients worldwide in 2021, which was an increase of 4.5% compared to 2020.
Materials and methods
The chest CT image data from 112 patients with pulmonary tuberculoma who were diagnosed clinically at Hang zhou Red Cross Hospital between October 16, 2013 and March 21, 2023were analyzed retrospectively.
Results
The average volumetric CT value of 108 active tuberculomas (33.39 [28.17,36.23] HU) was significantly lower than the average volumetric CT value of 64 inactive tuberculomas (78.91 [57.81,120.31] HU);the difference was statistically significant (Z = −10.888, P < 0.001).
Discussion
At present, the main basis for clinicians to judge active pulmonary tuberculosis by chest CT is based on the focus with ground-glass changes, the tree bud sign, the central lobular nodule sign, consolidation, and a thick-walled cavity.
Acknowledgments
We thank International Science Editing (http://www.internationalscienceediting.com) for editing this manuscript.
Citation: Wei G, Zhang J, Qiu X (2024) Application value of volumetric CT value in quantifying the activity of a pulmonary tuberculoma. PLoS ONE 19(8): e0306875. https://doi.org/10.1371/journal.pone.0306875
Editor: Jose Gerardo Tamez-Peña, Instituto Tecnológico y de Estudios Superiores de Monterrey: Tecnologico de Monterrey, MEXICO
Received: May 23, 2023; Accepted: June 25, 2024; Published: August 12, 2024
Copyright: © 2024 Wei et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: All relevant data are within the manuscript and its Supporting Information files.
Funding: This research received funding from the Zhejiang Provincial Health Science and Technology Plan Project (2021KY252). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.
Competing interests: No authors have competing interests.
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0306875#abstract0
